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research-grade insights for individual and family data

Get research-grade insights for your cases using state of the art agentic AI grounded in DNA and other biological data*.

*All information uploaded to Bystro must be de-identified. Bystro is intended for research, educational, and informational purposes only.

Explore Applications

See how you can use grounded AI for case-level analysis.

De Novo Variant Analysis

Family Trio Investigation

Analyze parent-child trios to identify de novo mutations. The platform filters inherited variants, highlights candidate pathogenic mutations, and provides clinical annotations in natural language.

  • Automatic inheritance pattern detection
  • ClinVar, OMIM, and gnomAD annotations
  • Exportable reports for review by clinicians

Investigate Individual Cases

Phenotype-Driven Analysis

Start with a phenotype and explore relevant genetic variants. Ask questions in plain language about metabolic pathways, drug metabolism, or disease associations.

  • Search phenotype/genotype associations
  • Pharmacogenomic variant interpretation
  • Literature references for findings

Supported Data Formats

Upload standard genomic file formats from any sequencing platform or genotyping array.

Whole Genome

WGS

VCF files from complete genome sequencing

Whole Exome

WES

VCF files from exome capture sequencing

Microarray

SNP Arrays

VCF exports from genotyping platforms

Other Formats

Flexible Input

Contact us for custom data formats

Research-grade insights

For professionals, educators, and curious learners.

Genetic Counselors

Explore variant significance and inheritance patterns when preparing case reviews.

Clinical Researchers

Investigate individual cases and generate hypotheses for further study.

Educators & Students

Learn genomics methodology hands-on with real data in classroom or self-directed settings.

Curious Learners

Explore your genomic data for educational purposes only. Any insights should be discussed with a medical professional, as the platform does not provide medical advice.

Looking for large-scale cohort analysis or enterprise features? Contact us..

Request Access

Join researchers and clinicians using grounded AI for individual genomic analysis.

Research Use Only

This platform is designed exclusively for research, educational, and exploratory purposes. It is not intended for clinical diagnosis, treatment decisions, or direct patient care. All findings should be validated through appropriate clinical workflows and reviewed by qualified professionals.