Access research-grade insights for individual and family data
Variant annotations across your favorite databases in seconds.
Discovery - Simple, Fast, Accurate
Get research-grade insights for your cases using state of the art agentic AI grounded in DNA and other biological data*.Filter inherited variants. Highlight candidate mutations. Get clinical annotations.
*All information uploaded to Bystro must be de-identified. Bystro is intended for research, educational, and informational purposes only.
Who it's for
Built for professionals who need grounded answers
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Genetic Counselors
Explore variant significance and inheritance patterns when preparing case reviews.
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Clinical Researchers
Investigate individual cases and generate hypotheses grounded in actual genetic data.
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Educators & Students
Learn genomics methodology hands-on with real data in classroom or self-directed settings.
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Curious Learners
Explore your own genomic data for educational purposes. Discuss insights with a medical professional.
Looking for large-scale cohort analysis? Contact us.
Research-grade genomic analysis
Your cases. Answered faster.
From de novo trios to variant lookups. Every finding grounded in your patient's data and cited literature.
Family Trio Investigation
De Novo Variant Analysis
Automatic inheritance filtering. Clinical annotations in plain language.
Analyze parent-child trios to identify de novo mutations. The platform filters inherited variants, highlights candidate pathogenic mutations, and provides clinical annotations in natural language.
- Automatic inheritance pattern detection across the trio
- ClinVar, OMIM, and gnomAD annotations on every candidate
- Exportable reports for review by clinicians
Phenotype-Driven Analysis
Investigate Individual Cases
From symptom to variant to published literature in one conversation.
Start with a phenotype and explore relevant genetic variants. Ask questions in plain language about metabolic pathways, drug metabolism, or disease associations.
- Search phenotype and genotype associations without writing queries
- Pharmacogenomic variant interpretation for prescribing decisions
- Literature references attached to every finding
Variant Lookup
Ask about any variant without uploading a single file.
ClinVar, gnomAD, OMIM, and the literature. One query.
A lab report comes back with a variant you want to know more about. Type the name and ask. Bystro pulls clinical significance, population frequency, associated conditions, and relevant published cases into a plain-language summary you can act on.
- Clinical significance, population frequency, and disease associations in one answer
- Pharmacogenomic implications surfaced where relevant
- Published case references attached so you can dig deeper if needed
Compatible
Supported Data Formats
Upload standard genomic file formats from any sequencing platform or genotyping array.
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Whole Genome
VCF files from complete WGS
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Whole Exome
VCF files from exome capture sequencing
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Microarray
VCF exports from genotyping platforms
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Other Formats
Contact us for custom data formats
Research Use Only — For research, educational, and informational purposes.
Not intended for medical diagnosis, treatment, or clinical use.