BYSTRO AIGENETICSGPT
Trio AnalysisPharmacogenomics

Vignettes

Real-world examples of using Bystro for genomic analysis. These vignettes show you how to approach complex genetic questions and leverage AI to get meaningful insights from your data.

Trio Analysis & De Novo Variant Discovery

What you'll see:

  • ▶Classic platform approach: subtract parent variants
  • ▶AI Smart Search with natural language queries
  • ▶Pathogenic variant identification and interpretation
  • ▶AI-guided analysis when family relationships unknown

Try these questions:

"Are there any pathogenic de novo variants? The child is [sample], and the parents are [sample1] and [sample2]."

"Are there any pathogenic de novo variants in this trio dataset?"

🧬 Perfect for family studies and identifying disease-causing variants

Pharmacogenomics & Drug Response Analysis

What you'll learn:

  • ▶Linking genetics to disease susceptibility
  • ▶Drug response prediction from genetic variants
  • ▶Alternative treatment recommendations
  • ▶Clinical conversation guidance

Example analysis:

"The person in the VIP dataset has early-onset frequent gout, could there be a genetic basis for this and is there any medication they may respond to differently based on their genetics?"

Important: Never make medical decisions based on these results. Always consult a doctor before making any health-related changes.

More Exciting Vignettes Coming Soon

What's Next

We're creating more powerful vignettes that showcase cutting-edge genomic analysis techniques. From population-scale GWAS studies to multi-omics integration, these upcoming examples will demonstrate how AI can transform complex research workflows into intuitive conversations.

Coming Up:

  • • Population genetics deep dives
  • • Advanced GWAS interpretation
  • • Multi-ancestry risk prediction
  • • Proteomics pathway analysis

Research Workflows:

  • • Clinical variant interpretation
  • • Longitudinal cohort studies
  • • Drug target discovery
  • • Rare disease investigation

Try These Approaches

These vignettes show real analysis patterns you can apply to your own data. Start with similar questions and adapt them to your research needs.

Start Smart Search

New to Bystro?

Learn the fundamentals with our step-by-step video tutorials covering data upload, AI queries, and platform navigation.

Watch Tutorials

Apply These Techniques

These vignettes demonstrate real analysis patterns you can use with your own data.The key is asking specific, well-formed questions that guide the AI toward the insights you're seeking. Start with similar queries and adapt them to your research questions.